scATAC + RNA-seq
Matched chromatin accessibility and gene expression from the same nucleus for integrated multi-omic insights.
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Introduction
One Experiment. Two Layers of Biology. Unlimited Insights.
Matched chromatin accessibility and gene expression from the same nucleus for integrated multi-omic insights.
Highlights
Matched Modalities per Nucleus
ATAC and RNA captured from the same cell
Random-Primed RNA Strategy
Enables full-length coverage and non-polyA RNA detection
Regulatory–Expression Integration
Supports mechanistic interpretation of gene regulation
Dual-Index Library Design
Minimizes index hopping and supports flexible sequencing modes
Workflow
From Sample to Insight in Seven Steps
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Prepare Nuclei
Fresh,frozen,or fixed samples
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Tn5 Transposition
Tag accessible chromatin
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Microfluidic Partitioning
Barcode ATAC and RNA from the same cell
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Pre-amplification
Pre-amplification of cDNA & ATAC fragments
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Library Prep
Construct ATAC and expression libraries separately
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Sequencing
Generate paired datasets
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Bioinformatic Analysis
View gene expression and chromatin accessibility together
Product Features
Supported Species
Sample Types
Components
Product Name
Product Code
Specification
SeekOne™ DD Single Cell Multiome ATAC + RNA Kit
K02901-08
8 tests
Components Name
Components Code
Specification
SeekOne™ DD Chip S3 Kit
K00202-0801
8 tests
SeekOne™ DD scFAST-seq Barcoded Beads Kit
K00801-0802
8 tests
SeekOne™ DD Single Cell DNA Tagmentation Kit
K02901-0801
8 tests
SeekOne™ DD Single Cell Multiome Droplet Reaction Kit (ATAC + RNA)
K02901-0802
8 tests
SeekOne™ DD Single Cell Multiome Amplification Kit (ATAC + RNA)
K02901-0803
8 tests
SeekOne™ DD Library Construction Kit
K00202-0804
8 tests
SeekOne™ DD Single Cell Cleanup Kit
K00202-0805
8 tests
Compatible Instrument
A high-throughput, automated single-cell multi-omics platform based on microfluidic water-in-oil technology for single cell/nucleus separation and barcoding.
Compatible Software
Data Analysis
SeekArc™ Tools
Analysis toolkit for SeekOne™ Multiome ATAC + RNA data, integrating chromatin accessibility and transcriptome quantification for joint downstream analysis.
SeekSoul™ Online
Cloud-based platform for single-cell multi-omics data analysis and visualization — zero code, full workflow, accessible anywhere.
Featured Resources
Access datasets, publications, and tutorials to accelerate your research
- Product List
- User Manuals
- Sequencing
- FAQ
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Demo Datasets
Products: scATAC + RNA-seq
Species: Mouse
Tissue Type: Brain
Sample State: Fresh
Products: scATAC + RNA-seq
Species: Mouse
Tissue Type: Skin
Sample State: Fresh
Products: scATAC + RNA-seq
Species: Human
Tissue Type: PBMCs
Sample State: Frozen
Products: scATAC + RNA-seq
Species: Mouse
Tissue Type: Colon
Sample State: Frozen
Publications
![[ Cellular and Molecular Life Sciences ]](https://omo-oss-image.thefastimg.com/portal-saas/pg2025082617304720158/cms/image/6c6ee98e-d6ac-436b-8cac-5700776329a0.png)
[ Cellular and Molecular Life Sciences ]
Myogenic enhancer snatching promotes adipogenic differentiation during epigenetic reprogramming mediated by lineage-specific transcription factors
2025 Nov.
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