scMethyl + RNA-seq
Simultaneous single-cell methylation and RNA profiling at single-base resolution for integrated epigenetic and transcriptional insights.
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Introduction
One Cell. A Complete Profile.
Simultaneous single-cell methylation and RNA profiling at single-base resolution for integrated epigenetic and transcriptional insights.
Highlights
Complete Multiomics
Integrated analysis of DNA methylation, transcriptome, V(D)J, and CNV.
Single-Cell Resolution
High-resolution profiling reveals true cellular heterogeneity beyond bulk averaging.
High-throughput
Capture tens of thousands of cells per run, enabling large-scale studies.
Broad Sample Compatibility
Compatible with nuclei or whole cells, fresh or frozen tissues, and blood.
Workflow
From Sample to Insight in Six Steps
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Sample Prep
Tissue dissociation & cell suspension QC
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Tn5 Tagmentation
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Microfluidic Partitioning
Barcode Methyl and RNA from the same cell
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Library Prep
Construct expression libraries and methylation libraries
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Sequencing
Generate paired datasets
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Bioinformatic Analysis
Analyze gene expression and methylation together
Product Features
Sample Types
Components
Product Name
Product Code
Specification
SeekOne™ DD Single-Cell Multiome Methylation+RNA Kit
K00901-08
8 tests
Components Name
Components Code
Specification
SeekOne™ DD Chip S3 Kit
K00202-0801
8 tests
SeekOne™ DD Cell Fixation and Nucleosome Depletion Kit
K00901-0801
8 tests
SeekOne™ DD Single Cell Multiome Purification Kit (Methyl+RNA)
K00901-0804
8 tests
SeekOne™ DD Single Cell Multiome Droplet Reaction Kit (Methyl+RNA)
K00901-0803
8 tests
SeekOne™ DD Single Cell 5' cDNA Amplification Kit
K00501-0806
8 tests
SeekOne™ DD Single Cell Nextera Library Prep Kit
K00901-0806
8 tests
SeekOne™ DD Single Cell DNA Methyl Library Prep Kit
K00901-0805
8 tests
SeekOne™ DD Single Cell Methyl Barcoded Beads Kit
K00901-0802
8 tests
Compatible Instrument
A high-throughput, automated single-cell multi-omics platform based on microfluidic water-in-oil technology for single cell/nucleus separation and barcoding.
Compatible Software
Data Analysis
SeekSoul™ Methyl Tools
Analysis toolkit for SeekOne™ Multiome Methylation + RNA data, integrating methylation and transcriptome quantification for joint downstream analysis.
SeekSoul™ Online
Cloud-based platform for single-cell multi-omics data analysis and visualization — zero code, full workflow, accessible anywhere.
Featured Resources
Access datasets, publications, and tutorials to accelerate your research
- Product Brochure
- User Manuals
- Sequencing
- FAQ
- Analysis
- Product Brochure
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- User Manuals
- Sequencing
- FAQ
Demo Datasets
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